The Science of Increasing Health and Longevity with Dr. Matt Kaeberlein

Thu, 11 Aug 2022 15:40:00 +0000

On average, humans are living longer than ever before, thanks in large part to modern medicine and biomedical innovations.

But those years, almost decades, of extra life are not necessarily spent in good health.

In short, while the human lifespan—how long we live—has increased, the average human healthspan, which is how long we actually live in good health, has not.

As we age, our risk of developing many different diseases goes up significantly. The data shows this to be practically inevitable. Whether it be some form of Alzheimer's disease, cardiovascular disease, oral disease, kidney disease, diabetes, cancer, the list goes on. The risk goes up.

Those extra years, those extra decades of life? There’s a good chance you’ll spend that time battling one disease or another.

But what if we could spend more of those extra years, decades in good health instead of relentless decline?

Our guest in this episode is Dr. Matt Kaeberlein, professor of Laboratory Medicine and Pathology at the University of Washington, where he's also the founding director of the Healthy Aging and Longevity Research Institute, and the founder and co-director of the well-known Dog Aging Project, one of main topics of discussion today.

Dr. Kaeberlein is one of the most respected leading scientists in the world today making the case that extending human healthspan is possible, given what the data from the latest research tell us.

We talk about the Dog Aging Project and Dr. Kaeberlein's quest to understand the biology of aging so that something can be done about it.

For all questions related to Dr. Kaeberlein's work, please send all questions and comments to our team here: https://bit.ly/3tHEIKR

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The Science of Regenerating Teeth and Restoring Smiles with Dr. Paul Sharpe

Thu, 14 Jul 2022 11:00:00 +0000

When we talk about living healthier for longer we must also include oral health, which plays a crucially important role in physical and mental health. According to the World Health Organization, over a billion people worldwide (~20% of the human population) experience trauma to their teeth at some point in their life, which can lead to tooth loss and lower quality of life.

Current treatments are costly, lengthy, and often require additional procedures throughout the patient's life, which can be financially and emotionally draining.

Scientists working on the dental regeneration technology (known as "Biotooth") aim to create a treatment that could regenerate your damaged or lost tooth using your stem cells.

We talk all about Biotooth with none other than Dr. Paul Sharpe, who is one of the pioneers and leaders in this field.

Dr. Paul Sharpe is head of the Department of Craniofacial Development and Stem Cell Biology at the historic King's College London, which is a wellspring of biomedical pioneers and innovation. As department head, Dr. Sharpe leads multiple academic research groups consisting of world-class biomedical researchers aiming to unravel the causes of diseases and translate discoveries into treatments to improve health worldwide.

Dr. Sharpe's research focuses on the molecular control of tooth development, dental stem cell biology, and stem-cell-based therapies in clinical dentistry. He's been at this for 30 plus years and counting, publishing over 300 research papers to date.

In 2004 Dr. Sharpe was awarded the Craniofacial Biology Research Award by the International Association for Dental Research, in recognition of his contribution to the understanding of how teeth develop. There's no one else better to talk with about this amazing Biotooth technology, which has the potential to restore smiles and improve an incredible amount of lives.

In this interview with Dr. Sharpe, we focus on how Biotooth came to be, its current status, where it's headed in the near future, and what needs to happen for it to become a clinical treatment.

For all questions related to Biotooth and Dr. Sharpe's work, please send all questions and comments to our team here: https://bit.ly/3tHEIKR